In
chemistry,
affinity chemistry was subject of study, dominant between 1718 and into the 1830s, that sought to explain
chemical reaction via various theories of chemical attraction or “
affinity”, such as
chemical affinity or
elective affinity, preexisting, in various levels, between all
chemical species or elements. [1]
History The name
affinitas was first used in the sense of chemical relation by Albertus magnus in circa 1250. What is called the "old theory" of
elective affinity tends to refer to the works of English chemist John Mayow (1674), French chemist
Étienne Geoffroy (1718), and Swedish chemist
Torbern Bergmann (1775). [2] It was Geoffroy, however, who made the first
affinity table (logic culled from Query 31 of
Isaac Newton's Opticks; thus establishing affinity chemistry as a branch of
science and invariably giving seed and momentum to the chemical revolution. [3]
Incorporation into modern theory In 1852, though the “theory of chemical valencies” of English chemist Edward Frankland, the degree of affinity attachment of each species was beginning to be incorporated into the soon-to-be science of quantum chemistry (1910s), solidifying eventually with American chemical engineer Linus Pauling’s 1928 article “On the Nature of the Chemical Bond”; and in the 1870s, the measure of
affinity was determined to be that of
free energy, thus incorporating this aspect of affinity chemistry into the new science of
chemical thermodynamics, and beginning [4]
Affinity chemistry is still to be found in modern science, albeit it is buried deep inside of connective theories of logic, such as affinity chromatography. [5] Likewise, in the modern
drug-receptor thermodynamic theory of “drug-receptor affinity”, affinity is defined as the “tendency of a drug
molecule to bind to a receptor”, a movement process quantified by intricate
Gibbs free energy models. [6]
Human chemistry German polymath
Johann Goethe based his 1809 romance novella
Elective Affinities on the work of
Bergmann, arguing a theory that human
relationships, specifically in reference to the passions of
love, are determined by
elective affinity preferences. [7] This publication thus founded the science of
human chemistry; albeit the modern version uses the logic of
chemical thermodynamics and quantum chemistry to argue the same view. [8]
References 1. (a) Comstock, John Lee. (1825).
A Grammar of Chemistry (section 49:
Affinity, pgs. 41-55). S.G. Goodrich.
(b) Turner, Edward and Bache, Franklin. (1830).
Elements of Chemistry (Section I:
Affinity, pgs. 102-114). John Grigg (publisher).
2. (a) Partington, J.R. (1937).
A Short History of Chemistry (pgs. 137, 322). Dover.
(b) Geoffroy, Étienne F. (
1718). Tableau des différentes Rapports Observées entre Différentes Substances (Table of the Different Relations Observed between Different Substances). France. (c) Bergman, Torbern. (1775).
A Dissertation on Elective Attractions. London: Frank Cass & Co.
3. Kim, Mi Gyung. (2003).
Affinity, That Elusive Dream – A Genealogy of the Chemical Revolution. Cambridge, Mass: The MIT Press.
4. Levere, T. (1993).
Affinity and Matter – Elements of Chemical Philosophy [1800-1865]. New York: Taylor & Francis.
5. Mohr, Peter and Pommerening. (1985).
Affinity Chromatography (section:
History of Affinity Chromatography, pgs. 7-18). CRC Press.
6.
Raffa, Robert B. (2001). Drug-Receptor Thermodynamics - Introduction and Applications (Section: Drug-Receptor Affinity, pg. 4). New York: John Wiley & Sons. 7. Goethe, Johann. (1809).
Elective Affinities. New York: Penguin Classics.
8.
Thims, Libb. (2007). Human Chemistry (Volume Two), (preview), (ch. 10: "Goethe's Affinities", pgs. 371-422). Morrisville, NC: LuLu.