
In
biochemical thermodynamics,
Ejnar Lundsgaard (1899-1968) was a Danish physiologist noted for his work in 1930 which showed that "nonlactic" muscle contractions can be made at the expense of the dephosphorylation of creatine phosphate. This work was carried on to a higher degree by his protégé
Herman Kalckar and by Kalckar’s correspondent
Fritz Lipmann who in 1941 introduced the theory of
ATP as a universal biochemical energy currency.
Education Lundsgaard was professor of physiology at the University of Copenhagen from 1934 to 1967. [2]
OverviewIn 1930, Lundsgaard made the important finding that frog muscles poisoned with iodoacetate and therefore unable to carry out glycolysis (the splitting of glucose to lactic acid) are nevertheless capable of carrying out a limited number of contractions. Lundsgaard later showed that these "nonlactic" contractions were at the expense of the dephosphorylation of creatine phosphate, which had been discovered and characterized only a few years earlier by American biochemist Cyrus Fiske at the Harvard Medical School. [1]
In 1934, newly-minted Danish physician
Herman Kalckar became Lundsgaard’s PhD student in the physiology department of the University of Copenhagen.
References1. Kennedy, Eugene P. (1991). “
Herman Moritz Kalckar (1908-1991)” – US National Academy of Sciences.
2.
Einar Lundsgaard (Danish → English) – The Comprehensive Danish: Gyldendals abne Encyclopedia.
Further reading● Lipmann, Fritz. (1969). “Einar Lundsgaard”,
Science, 164: 246-47.
● Kruhoffer, Poul and Crone, Christian. (1972).
Reviews of Physiology, Biochemistry, and Pharmacology, Volume 65 (
Ergebnisse der Physiologie Biologischen Chemie und Experimentellen Pharmakologie) (Ch:
Einar Lundsgaard, 1899-1968). Springer.
External links●
Lundsgaard, Einar (1899-1968) – WorldCat Identities.