In human thermodynamics, Georgi Pavlovich Gladyshev (1936-) (DN = 8-10) is a Russian physical chemist noted for his 1978 Gibbs free energy theory of evolution and sociology (sociological thermodynamics), both modeled on the movement of particles in the thermodynamics of chromatography, for his circa 1990s thermodynamic anti-aging theories of foodstuffs, and for his theoretical contributions to the development of human thermodynamics beginning in 2005. [1]

Overview
In his seminal 1978 article "On the Thermodynamics of Biological Evolution", Gladyshev argues that the methods of classical thermodynamics, conceived through a framework of hierarchical thermodynamics, in contrast to Prigoginean thermodynamics evolution models, regulates the process of the evolution of biological structure. [2]

This theory was written in direct opposition to the non-equilibrium thermodynamic evolution theory of Belgian chemist Ilya Prigogine, winner of the 1977 Nobel Prize in chemistry for his dissipative structure evolution theory in which biological structure is argued to self-assemble in thermodynamic systems far from equilibrium through the method of bifurcations and fluctuations. [3]

In 2007 and audio recording of Gladyshev lecturing at the American Association for Anti Aging Medicine (A4M) Conference in Las Vegas was recorded. [5]

Videos
The following is Gladyshev giving an overview of his theory in 2010:

2010 overview of Gladyshev's evolution theory. [4]

Thims
Beginning in 2005, Gladyshev began collaborating with American chemical engineer Libb Thims in the exchange of ideas and development of new theory. Gladyshev was of great influence to Thims, especially in construction and subsequent publication of his first two books, the 2007 Human Chemistry and the 2008 The Human Molecule. In December 2007, Thims and Gladyshev started the Encyclopedia of Human Thermodynamics.

Thermodynamic theory of the evolution of living beings

See main: Thermodynamic Theory of the Evolution of Living Beings

In 1997, Gladyshev published his 142-page book Thermodynamic Theory of the Evolution of Living Beings, in Russian and English, in which he set forth the first unified theory of the origin and evolution of living beings from the view point of thermodynamics, built on the chemical thermodynamics work of American mathematical engineer Willard Gibbs. [1]

The logic of Gladyshev's thermodynamics constitutes what he calls "hierarchical thermodynamics". This theory, to note, was in direct contrast to the more-established 1970s paradigm of the far-from-equilibrium dissipative structure theory of Belgian chemist Ilya Prigogine, who developed an “internal entropy” generation function model to account for the appearance of spontaneously forming ordered structures in the high heat flow regime of viscous mediums, such as the formation of Bénard cells in silicon oil placed on a hot plate, in which the heat is turned up past the turbulent flow regime.

Living systems evolution model
During the process of the evolution of the earth, according to Gladyshev, the existence of local equilibrium, within sub-systems of the biosphere, each being found surrounded by isothermal and isobaric thermostats, means that at times comparable with the periods of relaxation to equilibrium we deal with a set of thermodynamically closed microvolumes, i.e. an elementary volume that is still so large that it contains a great number of particles, constituting the phase under consideration. Within this phase, according to the laws of chemical thermodynamics, the integral value of the specific, i.e. averaged over the volume, Gibbs function corresponding to the formation of averaged local “evolved” conformation of aggregated supramolecular structures achieves a minimum:

Here, V is the volume of the system, m the mass of the selected microvolumes; x, y, and z the coordinates; the bar "–" means that the specific value is considered and the tilde "~" symbol indicating a heterogeneous system; the "im" superscript indicating the intermolecular component of the system.

Gladyshev's 1997 book, which explains evolutionary change via Gibbs' equilibrium criteria. [1]

Education

See main: Gladyshev: Biography

Gladyshev was born September 19, 1936 in Alma-Ata, Russia. In 1959, he graduated from the Chemistry Department of the State University in Alma-Ata in and in 1962 received the Degree of Candidate of Science (Ph.D.) and a Doctorate Degree in polymer chemistry in 1966. He became Professor of Physical Chemistry in 1969. In about 1975, Gladyshev began working on the problem of the thermodynamics of the macro-biological scale.

References
1. Gladyshev, Georgi, P. (1997). Thermodynamic Theory of the Evolution of Living Beings. Commack, New York: Nova Science Publishers.
2. Gladyshev, Georgi, P. (1978). "On the Thermodynamics of Biological Evolution", Journal of Theoretical Biology, Vol. 75, Issue 4, Dec 21, pp. 425-441 (Preprint, Chernogolovka, Institute of Chem. Phys. Academy of Science of USSR, May, 1977, p. 46).
3. Prigogine, Ilya. (1977). "Time, Structure, and Fluctuations", Nobel Lecture (in chemistry), Dec 08.
4. Georgi, Gladyshev and Thims, Libb. (2010). “Georgi Gladyshev | Thermodynamics of Evolution”, YouTube, Mar 18.
5. Gladyshev, Georgi. (2007). “Hierarchical Thermodynamics: Quality Food and Medicine”, A4M Las Vegas, Dec 12, 9:00 am – 12:00pm, 27m 03s, 36 slides (PDF or MP3).

Further reading
● Newspaper interview (1999) with Prof. Georgi P. Gladyshev (correspondent Mr. A. Gubanov).
● Gladyshev, Georgi P. (1999). "On Thermodynamics, Entropy and Evolution of Biological Systems: What Is Life from a Physical Chemist's Viewpoint." Entropy 1, no. 2: 9-20.
● Gladyshev, Georgi P. (2005). “The Second Law of Thermodynamics and the Evolution of Living Systems”, Journal of Human Thermodynamics, Vol. 1, pgs. 68-81, December.
● Gladyshev, Georgi P. (2007). “Leonhard Euler’s Methods and Ideas Live in the Thermodynamics Hierarchical Theory of Biological Evolution.” International Journal of Applied Mathematics and Statistics, Nov., Vol. 11, No. N07, pgs. 52-68.
● Gladyshev, Georgi P. (2009). “Life is characterized by Spontaneous and Non-spontaneous Transformations in Living Quasi-closed Thermodynamic System.” Google docs. Nov. 17.
● Gladyshev, Georgi. (2009). “Love: our Life – Thermodynamics and Love” (Russian → English), Knol, Jun 21.
● Gladyshev, Georgi. (2010). “On the Thermodynamics of the Evolution and Aging of Biological Matter.” Journal of Human Thermodynamics, 6: 26-38.

External links
● Georgi Gladyshev - Biography Overview
● Georgi Gladyshev - A4M Conference Library, Speaker Profile
● Georgi Gladyshev - My Science Life, A Wetpaint Wiki
● Georgi Gladyshev - Wikibin