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Irving M. KlotzIn chemical thermodynamics, Irving M. Klotz (1916-2005) was an American professor of chemistry and biochemistry, molecular biology and cell biology, notable for the publication of his 1950 textbook Chemical Thermodynamics – Basic Theory and Methods, one of the first teaching books on the subject of chemical thermodynamics. [1]

In following editions of the textbook, which is still in use, Klotz began to co-author with Robert M. Rosenberg. [2] Klotz received his bachelor’s degree in 1937 and completed a PhD in 1940, both from the University of Chicago, after which time he joined the faculty of Northwestern University, in Evanston, IL, where he guided the development of the application of thermodynamics into the biological sciences, particularly in the area of ligand-receptor energetics. [3]

● Klotz, Irving M. (1997). Ligand-Receptor Energetics. Wiley.
● Raffa, Robert B. (2001). Drug-Receptor Thermodynamics, (ch. 3: “Thermodynamic Concepts: Evolution and Application”, pgs. 31-54, by Irving M. Klotz, ch. 7: “Effector-Receptor Interactions: Origin and Development of Energetic Perspectives”, pgs. 105-125, by Irving M. Klotz). Wiley.

1. Klotz, Irving M. (1950). Chemical Thermodynamics – Basic Theory and Methods, New York: Prentice-Hall, Inc.
2. Klotz, Irving M. and Rosenberg, Robert M. (2008). Thermodynamics – Basic Theory and Methods, (7th ed). Wiley-Interscience.
3. Staff writer. (2005). “Irving M. Klotz Dies at Age 89”, Northwestern News, May 03.

External links
Symposium Honors Irving Klotz, Northwestern University.

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