Cover of the 1957 Energy Transformations in Living Matter, by Hans Krebs, Hans Kornberg, and Keith Burton, the first book on the thermodynamics of living matter. |
“To apply thermodynamics to the problem of how life got started, we must ask what net energy and entropy changes would have been is simple chemical substances, present when the earth was young, were converted into living matter [as in the formation of a mouse] … to answer this question [for each process], we must determine the energies and entropies of everything in the initial state and final state.”
“There are living systems; there is no living ‘matter’. No substance, no single molecule, extracted and isolated from a living being possess, of its own, the aforementioned paradoxical properties. They are present in living systems only; that is to say, nowhere below the level of the cell.”— Jacques Monod (1967) (Ѻ)