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ReactionMatch.com

Sadi-Carnot — Mon, 01 Dec 2008 22:29:31 CST

In human chemistry, ReactionMatch.com is a beta-phase science-based online dating site situated on the premise of “matching affinities in love the chemical reaction” using the 1809 human romantic elective affinities matching theories of German polymath Johann von Goethe. [1]

The modern variation of this branch of science was outlined, in both social and online-matching terms, in American chemical engineer Libb Thims’ 2007 textbook Human Chemistry. [2] Many of the basic principles of this type of matching are being discussed in the new 2008 YouTube educational channel Human Chemistry 101. [3] The shortened logic behind the a unified theory of human pair-matching is:

“Matching people, in love the chemical reaction,

to obtain successful lasting relationships

using the same proven methods

of how atoms and molecules are matched.”

Overview
In modern terms, affinity-matching equates to the determination of optimized relationship pairings and marriages using the chemical thermodynamics logic of “free energy compatibilities”, in which “free energy” is considered as the measure of the “work” output, or the amount of energy going inward or outward of the functionality of the union, of the relationship over time. In particular, it was German physician and physicist Hermann Helmholtz who proved in 1882 that free energy is "the true measure of the affinity of a chemical reaction." [4]

In short, the measure of the free energy change in a pairing determines whether the relationship will work or not over the “extent” of the hypothetical reaction (pairing). Subsequently, as 66% of people believe that love is a purely chemical reaction, a realistic matching site algorithm would need to incorporate a theory of pairing human chemical reactions according to the standard spontaneity criterion of chemical energetics. [5]

The website Ulteem.com, to site one example of this type of application, uses a 98-question compatibility test that matches what they define as “compatibility/affinity” between prospective mates and ranks resultant potential mates according to “affinity” percentages, such as “you have 77% affinity with this woman" and "a 65% affinity with that women”, etc. [6] The use of the word affinity here, however, seems to be only metaphor. The Ulteem.com example, is give here to illustrate that someone from the hard science community needs to step up to the plate and to put some rigor (physics, chemistry, thermodynamics) into matching algorithms for the betterment of humankind. This is where ReactionMatch.com will fit in. On this premise, Reaction Match is scheduled to become a leader in the next-generation of online scientific matching.

Beta-stage
Currently, ReactionMatch.com is in development. The idea of a chemical thermodynamics based mate selection theory was conceived in the mind of American chemical engineer Libb Thims in 1995, seeded, in part, by the 1994 book The Evolution of Desire by American evolutionary psychologist David Buss, based on the logic of reaction prediction found within standard thermodynamic free energy tables. See the RM history section for further details. The outline of how to set up human free energy tables was described by Thims (see: RM theory section) in the 2007 textbook Human Chemistry, section: “Human affinity (Gibbs free energy) Tables”. [7]

The push to begin taking this from theory to application, in the mind of Thims, came into view with the launching of the recent “chemistry-themed” pair matching sites, in particular eHarmony (2000), Chemistry.com (2006), eChemistry.com (2006), and ScientificMatch.com (2007), among others, who all freely popularize claims to be able to create “chemistry”, either physical, romantic, or interpersonal, between couples through matching algorithms (mostly psychological-based) of various kinds. These types of loose, unsubstantiated, or non-theoretically-based claims, in modern terms, of being able to create “chemistry” between people, using an algorithm, are comparable to the ancient alchemical claims of being able to create “gold”, using a philosopher’s stone, or to create "love", i.e. get someone to fall in love, using a love potion.

In 1661, Anglo-Irish chemist Robert Boyle, one of the founders of modern chemistry, for instance, had to point out to all the alchemists that what they were doing, with all their false claims, was detrimental to the betterment of the science of chemistry: [9]

“If men would more carefully distinguish those things that they know from those that they ignore or do but think, and then explicate clearly the things they conceive they understand, acknowledge ingenuously what it is they ignore, and profess so candidly their doubts, that the industry of intelligent persons might be set on work to make further enquiries, and the easiness of less discerning men might not be imposed on.”

In apology for being so sharply abrupt, Boyle continues ‘I perceive that [various] of my friends have thought it very strange to hear me speak so irresolvedly, as I have been wont to do, concerning those things which some take to be the elements, and others to be the principles of all mixt bodies.’ Here, Boyle is criticizing earlier research founded on the belief that salt, mercury, and sulphur were the ‘true principles of things’. The extrapolation, in modern terms, is that psychological matching is not the true ‘mystery of romantic chemistry’.

Subsequently, ReactionMatch.com, themed to be a hard-science upgrade from the softer forerunners (see: RM projections), is currently in the beta-stage of development (possibly being launched in 2010-12, or later), focused presently on: venture capital locking (possibly) and pilot plant site development and testing. The RM operations team is currently being assembled, under the coordination of Libb Thims, and development of the RM project is commencing via the secure RMbeta.pbwiki.com Intranet. [8]

References
1. (a) ReactionMatch.com – (draft porthole)
(b) ReactionMatch.com – WHOIS registry information.
(c) See: Goethe's human chemistry
(d) Tantillor, Astrida O. (2001). Goethe's Elective Affinities and the Critics. New York: Camden House.
(e) Adler, Jeremy. (1987). “Eine fast magische Anziehungskraft”. Goethe’s “Wahlverwandtschafte” und die Chemie seiner Zeit (“An almost Magical Attraction”). Goethe’s Elective Affinity and the Chemistry of its Time), Munich.
(f) Adler, Jeremy. (1990). "Goethe's use of chemical theory in his Elective Affinities" (ch. 18, pgs. 263-79) in Romanticism and the Sciences - edited by Andrew Cunningham and Nicholas Jardine, New York: Cambridge University Press.
(g) Thims, Libb. (2007). Human Chemistry (Volume Two), (ch. 10: "Goethe's Affinities", pgs. 371-422), (preview), (Google books). Morrisville, NC: LuLu.
2. (a) Thims, Libb. (2007). Human Chemistry (Volume One), (preview), (Google books). Morrisville, NC: LuLu.
(b) Thims, Libb. (2007). Human Chemistry (Volume Two), (ch. 10: “Goethe’s Affinities”, pgs. 371-422, ch. 12: Affinity and Free Energy” [section: “Online Matching”, pgs. 455-64], pgs. 423-68). (preview), (Google books). Morrisville, NC: LuLu.
3. Human Chemistry 101 - YouTube
4. (a) Helmholtz, Hermann. (1882). “Die Thermodynamik Chemischer Vorgänge (The Thermodynamics of Chemical Operations”, SB: 22-39, in Wissenschaftliche Abhandlungen von Hermann von Helmholtz. 3 vols. Leipzig: J.A. barth, 1882-95. 2:958-78.
(b) Young, Paul T. (1936). Motivation of Behavior – the Fundamental Determinants of Human and Animal Activity, (ch. 2: “The Energetics of Activity”, pg. 68) New York: Wiley.
5. Thims, Libb. (2005). "Poll: Is Love a Chemical Reaction?", Research Project #4, Chicago: Institute of Human Thermodynamics.
6. Ulteem.com – Motto: Your future awaits you.
7. Thims, Libb. (2007). Human Chemistry (Volume Two), (ch. 11, section: “Online Matching”, pgs. 455-64; section: “Human Affinity (Gibbs free energy) Tables”, pgs. 464-68). (preview), (Google books). Morrisville, NC: LuLu.
8. ReactionMatch.com secure wiki (beta) - BPwiki.com.
9. Boyle, Robert. (1661). The Sceptical Chymist, (pg. 11). New York: Dover.

Libb Thims

Sadi-Carnot — Mon, 01 Dec 2008 22:03:39 CST

In science, Libb Thims is an American chemical engineer, electrical engineer, and thermodynamicist known for his work and research in the areas of human chemistry and human thermodynamics. Thims' central interest, which began as a chemical engineering student in 1995, is to understand how human relationships work or operate energetically according to the science of chemical thermodynamics, in particular human chemical reaction prediction using the logic of spontaneity as embodied in free energy tables. Thims maintains one of the world's largest thermodynamics book collections.

Overview
In 2002, in efforts to coordinate writings on the thermodynamic study of human life, Thims founded the Institute of Human Thermodynamics, a non-profit, educational-minded, global network of human thermodynamicists. In 2005, Thims started the Journal of Human Thermodynamics, ISSN 1559-386X, a place for publication of articles on the thermodynamics of human life. In 2007, Thims and Russian physical chemist Georgi Gladyshev started the Encyclopedia of Human Thermodynamics.

Human Chemistry (2007)
The Human Molecule (2008)

Human Chemistry (2007)

The Human Molecule (2008)

In September 2007, building on the shoulders of Johann von Goethe, with his 1809 Elective Affinities, and American navel engineer William Fairburn, with his 1914 booklet Human Chemistry, Thims published Human Chemistry (Volume One) and Human Chemistry (Volume Two), the world's first-ever standardized textbook on human chemistry (824-pages). [1] In March of 2008, Thims published his second book The Human Molecule, a short outline of the historical development of the conception of the human being as an individual ‘molecule’, beginning with the coining of the term in 1869 by French philosopher Hippolyte Taine; followed by the first rudimentary social, economic, and historical theories using the human molecule concept as developed in the early 20th century by those as Leon Walrus, Vilfredo Pareto, Henry Adams, and C. G. Darwin; ending with a discussion of the first calculation of the molecular formula for a human being in 2000 by American limnologists Robert Sterner and James Elser.

Thims ideas on human thermodynamics and human molecules were developed in a duplicate manner, but independent, to those of American historian Henry Adams (1910) and English physicist Charles Galton Darwin (1952).

Side projects
YouTube's Human Chemistry 101 channel was started in 2008 by Thims, scheduled as a semi-weekly educational video series on the chemistry of human interactions. Thims is currently involved in the algorithm development of the 2012 beta-stage, science-based pair-matching site ReactionMatch.com (logo shown below), motto: “matching affinities in love the chemical reaction”. Other related dating/matching sites, by comparison, are slowly being categorized by Thims at the new DatingSitesWiki.

Short history of thermodynamic interest

See main: Libb Thims (history) and Human Chemistry (textbook) (origin)

Thims originally had developed his interest or rather curiosity about the potential chemical thermodynamic operation of human life in 1995, while an undergraduate chemical engineering student in a senior level thermodynamics class at the University of Michigan. During this course, he began to wonder if anyone had ever applied the logic of chemical reaction prediction, as embodied in standard thermodynamic tables of free energies, enthalpies, and entropies, to the extrapolative prediction of human chemical reactions, such as between potential intimate pairs in reproductive reactions?

Gladyshev and Thims

See main: Gladyshev and Thims

Of significant influence to Thims, was the work of Russian physical chemist Georgi Gladyshev. [2] In particular, sometime between 2002 to 2004, during which Thims began to undertake the project of writing a short book on the subject of "human thermodynamics", Thims had come across a number of individuals who seemed to be using a similar logic, in certain respects, to his own, including: Ilya Prigogine, John Avery, Jing Chin, David Hwang, and Gladyshev, among others. In this group, Gladyshev seemed to be the closest competion in that he was using a fully-rigorous Gibbs free energy based thermodynamic approach to the evolution of life.

Education
BS Chemical Engineering - University of Michigan
BS Electrical Engineering - University of Michigan
MS Physics/PhD Biochemistry/MD Neuroscience (all in progress)

Publications
● Thims, Libb. (2008). “Human Thermodynamic Imaging” (3-pgs), Vibraimage Wiki, Nov. 19.
● Thims, Libb. (2008). “Notes on Equilibrium Variants of Life”, (3-pgs), Scribd.com, Nov. 18.
● Thims, Libb. (2008). “Human Thermodynamics”, (3-pgs), Knol.Google.com, Oct. 01.
● Thims, Libb. (2008). The Human Molecule, (120-pgs). Morrisville, NC: LuLu.
● Thims, Libb. (2008). “On the Mechanical Equivalent of Heat and Occupation”, Journal of Human Thermodynamics, Vol. 3, Issue 1. pgs. 1-7, April.
● Thims, Libb. (2007). Human Chemistry (Volume One), (preview), (392-pgs). Morrisville, NC: LuLu.
● Thims, Libb. (2007). Human Chemistry (Volume Two), (preview), (436-pgs). Morrisville, NC: LuLu.
● Thims, Libb. (2005). “Evil, Structural Stability, and Predisposed Movements”, Journal of Human Thermodynamics, Vol. 1, Issue 1, pgs. 1-12. August.

Awards
● G. Brymer Williams Academic Scholarship (chemical engineering) of $1000 (University of Michigan).
● Elected in 2006 as member-correspondent of the International Academy of Creative Endeavors. [3]
● Awarded the 2008 medal Order of Mikhailo Lamonosov (adjacent), National Committee of social - public premium, Russia, N 104 (148).

Citations and conferences

See main: Libb Thims (citations)

Thims' work and theories, beginning in 2006, have been referenced and discussed in several journal articles, magazines, conferences, symposiums, and meetings as listed in the attached link.

Unfinished manuscripts
The following collection of manuscripts were only written in rough-draft, single pass, outline form, totalling about 1,100 pages. Copies, numbered up to a dozen, for the human thermodynamics series, and up to one-hundred, for the cessation thermodynamics manuscript, were printed and bound by hand and distributed locally around Chicago (primarily) for feedback and first impression:

Thims, Libb. (2005). Cessation Thermodynamics. 100-pgs. Chicago: Institute of Human Thermodynamics
Thims, Libb. (2004). Human Thermodynamics (Volume Three). 330-pgs. Chicago: Institute of Human Thermodynamics
Thims, Libb. (2003). Human Thermodynamics (Volume Two). 330-pgs. Chicago: Institute of Human Thermodynamics
Thims, Libb. (2002). Human Thermodynamics (Volume One). 330-pgs. Chicago: Institute of Human Thermodynamics

Unfinished articles
● Thims, Libb. (2006). “Neural Processing Unit Theory”, (left un-finished). Journal of Human Thermodynamics, Vol. 2, Issue 1, pgs. 1-10. Oct.
● Thims, Libb. (2005). “On the Nature of the Human Chemical Bond”, (left un-finished). Journal of Human Thermodynamics, Vol. 1, Issue 5, pgs. 36-67. December.

References
1. (a) Thims, Libb. (2007). Human Chemistry (Volume One), (preview). Morrisville, NC: LuLu.
(b) Thims, Libb. (2007). Human Chemistry (Volume Two), (preview). Morrisville, NC: LuLu.
(c) Press release: World’s first-ever textbook on the Chemistry of Love - September 27, 2007, 3:00 EST (PR.com)
(d) The entire writing project took 18-months and 14-days to complete.
2. (a) Gladyshev, Georgi, P. (1978). "On the Thermodynamics of Biological Evolution", Journal of Theoretical Biology, Vol. 75, Issue 4, Dec 21, pp. 425-441.
(b) Gladyshev, Georgi, P. (1997). Thermodynamic Theory of the Evolution of Living Beings. Commack, New York: Nova Science Publishers.
3. List category: “Leading representatives of foreign science” (English) (Russian) – International Academy of Creative Endeavors.

External links
● Libb Thims – LibbThims.com
● Libb Thims (LinkedIn)
● About :: Libb Thims – Institute of Human Thermodynamics
● Libb Thims’ Storefront (books) – LuLu.com
● Libb Thims - Open Library.
● Libb Thims’ T-Shirts and Posters – Zazzle.com
● Libb Thims’ All-Time Favorite Self-Derived Quotes – HumanThermodynamics.com

ReactionMatch.com (theory)

Sadi-Carnot — Mon, 01 Dec 2008 21:46:33 CST

In human chemistry, the theory behind the concept of ReactionMatch.com, the chemical thermodynamics based pair matching site, is to match people (human molecules) to obtain successful or energetically feasible reactions (relationships) using the very same methods that are used to match atoms and small molecules in chemical reactions. [1] This theory was originally developed in 1809 by German polymath Johann von Goethe, which he called "elective affinities", otherwise known as the world's first chemical treatise on the origin of love. [2]

In modern terms, the first to develop Goethe's premise of elective affinity reactions occurring between humans and thus determining their mate and friendship preferences, was American chemical engineer Libb Thims, who in 1995 began to mediate on issue of chemical thermodynamics based mate selection, which in 2007 led to the publication of the world's first textbook on human chemistry (Human Chemistry), the study of the chemical behaviors of human molecules. [3]

Human chemical reaction engineering (HCRE) is the technical name of this emerging discipline, in which people (human molecules), i.e. reactants (A, B, C, etc.), are funneled through online matching algorithmic reactors to achieve desired products, i.e. stable dihumanide molecules (A=B, C≡D, etc.). [14] The first published, albeit in a humorous-style, outline of this logic was the Gibbs free energy thermodynamics of love theory describe by American computational chemist David Hwang in his 2001 article "The Thermodynamics of Love". [4]

Continuous flow algorithmic reactors
A continuous flow algorithmic reactor (CFAR) is the technical name of an online matching site that uses science-based algorithms to match people, by design, in desired reactions, as shown adjacent. The basic CFAR design, of chemical thermodynamics-based online matching, is modeled on the standard continuous-flow reactor design variations. [14]

In this model, the input flow consists of single human particles or human molecules (A, B, C, ..) entering the matching site as "reactants". The output flow or "products" consists of two streams: (1) outflow of singles (C, D, ...) that didn't match and (2) outflow of paired couples (A=B, E≡F, ...) that did match. The time, i.e. number of days or months, in which a person is in a CFAR, as a paying subscriber of an online matching site, in the form of an unattached single, is called the “residence time”.

Matching theory overview
The basic idea behind scientific pair matching, from a chemical thermodynamic perspective, which is the science that determines the feasibilities of chemical reactions, is to pair people, considered as “human molecules”, such that successful reactions (relationships) lead to a stabilization in the bond A≡B, over the extent of the reaction, a factor quantified by a decrease in the free energy in the functionality and system of the relationship. This logic has successfully been applied to the chemical matching determinations for reactions between chemical species of size 6-elements in composition or less, as sizing criterion that can be discerned via molecular evolution tables (below). For larger chemical species, such as human molecules, a 26-element molecule, the same logic applies, however the matching determination (reaction feasibility) calculations are more difficult, but invariably reduce to enthalpy-entropy determinants (among other factors). In step-by-step terms, the matching of people (human molecules), in algorithmic terms, equates to the following:

a. Matching people is the process of setting up “potential” chemical (combination) reactions between individuals.
b. From a physical chemistry point of view, the overall “criterion” to predict the successfulness, spontaneity, or feasibility of any chemical reaction or of the matching any two chemical entities, is based on the criterion of energetics.
c. Technically, this means that at the start of a successful pairing, there exists a great deal of stored chemical potential energy, i.e. the relationship has “great potential”, and thus will continue reacting as it burns its working potential over the “extent” of the reaction.
d. The release of “working energy” (G), out of the bond of the relationship and into linked systems of friends, family, associations, and society, in a virtuous manner, over the course of a successful or spontaneous reaction, is quantified by decrease in the Gibbs free energy of the pairing: this is called thermalization or equilibration.
e. Successful thermalization processes, are those that continue to react into and past the golden anniversary (50+ years of happy marriage).
f. The point at which a relationship “stops working”, however, signifies a point in time in which the reaction is at equilibrium wherein the chemical potential is spent (a fact quantified in 1876 by American mathematical engineer Willard Gibbs).
g. The equilibrium point is typically when couples begin to break up, through what is called a dissociation reaction.
h. In extrapolation, the “overall criterion” to the successfully matching of individuals in relationships is an energetic one, meaning that individuals have to be matched energetically (criterion: ΔG < 0 for the paring); the mechanism has to match the laws of thermodynamics.
i. This can be quantified in terms of a per unit (A, B, AB, etc.) 12-factor free energy function, G = f(t), a dynamic function of time t, comprised of physical and neurological mate desireability attributes:
G = f(averageness, age, symmetry, sexuality, i.e. testosterone-to-estrogen ratios, immune system, i.e. MHC-determinants, fitness, complexion, personality, social graces, character, dependability, occupation, possessions, wealth, information, intelligence, education, knowledge, status, prestige, inner nature, values, and ambition, among others).
j. Each G = f(t) function, representing a person's (A) or couple's (AB) quantifiers, must then be translated in terms of the thermodynamic energy quantifiers of enthalpy H (the heat of reaction) and entropy S (the irreversible energy loss of reaction), i.e. G = f(H,S) according to the definition equation: G = H - TS, where T is the absolute temperature of the reaction system.
k. These G = f(t) energetic quantifications of individual persons can be used to determine pair feasibility for combination reactions (scientific matchings).

Matching example
To explain further, by example, suppose that person A was to be hypothetically paired up with three potential mates (B, C, D):

Couple pairing #1:

A + B → AB

Couple pairing #2:

A + C → AC

Couple pairing #3:

A + D → AD

The question then becomes, how would one use the logic of chemical thermodynamics and its ability to predict reactions, according to the spontaneity criterion (ΔG < 0), to help them determine who they should date or marry? In other words, which of the above reactions would be more spontaneous and thus more energetically favored? The answer is that each potential reaction, will have a different value of free energy change, ΔGAB, ΔGAC, and ΔGAD; subsequently, for the three potential matches, the one that has the largest negative value will be the best match.

Graphical analysis
In order to formulate the above human chemical thermodynamics matching scheme into a mate-selection algorithm, a first-step graphical analysis is needed. A first approximation match would be to determine feasible 20-year human chemical reactions, thus besting the current national average for divorce rates, in the US, which currently stands at 43% at 15-years. [5] In other words, according to the US National Center for Health Statistics, forty-three percent of first marriages break within fifteen-years. [6] Scientifically, from the get-go, marriages, i.e. unions (reactions), that end quickly in divorce are “less thermodynamically stable” than as compared to more energetically-favored marriages (reactions) that continue to ignite for 50-years or more.

Using chemical thermodynamics, it is changes in the value of free energy that are used to determine if a reaction is thermodynamically favorable. [7] The change in Gibbs free energy ΔG for a chemical reaction (human chemical reaction or otherwise) is defined by the following expression:

ΔG = GF – GI

in which GF is the instantaneous value of the free energy at the hypothetical final stage of the reaction and GI is the initial value at the collision point of the reaction.

Collision theory
The collision point, according to collision theory, is the point in time at which the two particles “collide” or first begin to have an interaction. The typical example being love at first sight, in which a visual field particle stimulus triggers the formation of a marriage bond (human chemical bond). About 20% of people will fall in love at first sight and marry that person. [8]

Subsequently, in the above set of hypothetical reactions, 1, 2, or 3, between the collision point (day-one) and the extent of reaction goal (20-year point), we will have three possible “initial” free energy GI values (GA+B, GA+C, GA+D) and three possible “final” free energy GF values (GAB, GAC, and GAD), which together yield three different calculated values of free energy change ΔG, namely: ΔGAB, ΔGAC, and ΔGAD, which are shown on the adjacent “free energy” vs. “extent” of reaction plot.

Activation energy barrier
In this diagram, the activation energy barrier represents the amount of "activation energy" EA that the potential couple must possess in terms of congruent arrangements of kinetic energy (entropy of activation; enthalpy of activation) at the point of collision, in order to surmount the activation energy barrier. This is an important factor that must be accounted for in any matching algorithm. [9] At the height of the activation energy barrier, the couple would be at a high energy state called the “activated complex” A - - - B, in which both their old bonds (family, friends, and associated networks) and newly forming bonds (attachment structure of the newly forming family, friends, and extended network) are stretched to their maximum. The entity that emerges on the other side of the activation energy barrier is the attached couple or “dihumanide molecule” connected through what is called a “human chemical bond” A≡B.

Spontaneity criterion
In this diagram we have four possible outcomes depicted, namely relationships A≡X, A≡B, A≡D, and A≡C positioned at various levels of Gibbs free energy. The best relationship outcome, namely the one that is the most stable, is determined by the spontaneity criterion, which is:

ΔG < 0 – the reaction is spontaneous in the forward reaction
ΔG > 0 – the reaction is nonspontaneous (the reaction is favored in the opposite direction)
ΔG = 0 – the system is at equilibrium (there is no net change)

Hence, in the hypothetical results depicted in the diagram, if a matched pair ended up at life position A≡X, above the relationship equilibrium level, the positive value of ΔG would be the amount of energy (work energy) that the pair would have to “put into” it to keep their relationship going, i.e. they would have to spend a lot of time and energy "working on their relationship" (a draining process), e.g. energy loss in friction, tension, arguments, disagreements, counseling, extended family strains, etc.

Conversely, positions below the relationship equilibrium level, namely A≡B, A≡D, and A≡C, are energetically favored and thus would each be, in theory, spontaneous reactions (relationships). The amount of “free energy”, in this case (ΔG < 0), in the words of American chemist Raymond Chang, is “the energy available to do work”. [11] In other words, it is the amount of the working energy of the relationship that is released out of the functionality of the human chemical bond of the pair, as they thermalize off each other, being used to do virtuous activity in life, in accordance with the progress of evolution.

The question then becomes: which of these three spontaneous reactions is the most favored? The answer to this is that the reaction that yields the most negative free energy change, will be the most spontaneous and thus the most energetically favored pairing. In the reaction situation: ΔGX < ΔGY < ΔGZ < 0, for instance, the reaction defined by the large negative value of "ΔGX" would indicate this to be the most favored reaction. A chemical bonding of this type, will be the most stable in the long term owing to the fulfillment of "quantum neurochemical octet rule bonding satieties" (drive/dream fulfillment) of the pair. [1] In the above example reaction, pairing A≡C is most-favored over the others.

Difficulties on theory
Beyond this basic outline, the greater difficulties involved in creating a computerized free energy compatibility based matching algorithm, is the mathematical translation of input values:

Physical data:
Genetic disease markers (e.g. Down syndrome), MCH-characteristics (immune-system compatibilities), blood types (blood sample processing), pupil-to-iris ratios, body-fat-percentages, measurements (height, weight, hair color, eye color, skin tone, etc.), beauty (physical attractiveness ratings, both unique and consensus), fitness, age, complexion, ethnicity, sexuality, waist-to-hip ratio, symmetry measurements.

Neurological data:
Personality patterns (explorer [dopamine], builder [serotonin], director [testosterone], negotiator [estrogen], etc.), occupation, Wealth, (possessions), intelligence, education, knowledge, status, prestige, drive, inner nature, values, ambition

Environment data:
Birth order, extended family networks, external forces, geographical momentum tendencies.

Among other data input sets, such as the 60-mate trait desireability factors, these total inputs need to be formulated into enthalpy ΔH and entropy ΔS terms in the standard Gibbs free energy function: [12]

ΔG = ΔH – TΔS

Beyond this, system particle flow (new human molecules into or out of a system), as quantified by changes in chemical potential μ of the system, and external forces, e.g. job loss, divergences in goal paths, the strain of a war, extended family factors, etc., need to be accounted for. In addition, emotional imaging processing would need further development to determine video (and in person) positive-to-negative Gottman stability ratios. [1]

Corroboration
The theory of matching human molecules (people) according to "free energy compatibilities", developed by Thims, not only finds excellent corroboration with the chemical-thermodynamic love-theories of those as Johann von Goethe (1809), William Fairburn (1914), George Carey (1919), Jeremy Adler (1987), David Hwang (2001), Chanel Wood (2007), but also with the recent thermodynamic evolution theories of Russian physical chemistry Georgi Gladyshev (1978), who in his 1997 book Thermodynamic Theory of the Evolution of Living Beings set forth the view, among others, that:

(a) The definition of ΔG is the energetic measure of system structure formation in a given system evolution relaxation window.
(b) Only the initial and final states of a process under study are of interest.
(c) The variations of the Gibbs function of the system, at any stage of evolution, particularly ontogenesis and philogenesis, can be calculated by thermodynamic methods.
(d) A function Gsystem-formation = f(t), can be obtained using thermodynamical data, thus representing the “state” of the system at a fixed moment in time.
(e) Variations of calculations of ΔG characterize stability changes in the system.

In review of the RM chemical thermodynamic based theory of mate selection, using a free energy compatibility methodology, as outlined above, Gladyshev states that he: "agree[s] with [the] propositions" ... and "this is a good practical application of [Thims] theory." [13]

See also
● ReactionMatch.com (projections)
● ReactionMatch.com (history)
● ReactionMatch.com (operations)

References
1. (a) Thims, Libb. (2007). Human Chemistry (Volume One), (preview), (Google books). Morrisville, NC: LuLu.
(b) Thims, Libb. (2007). Human Chemistry (Volume Two), (ch. 10: “Goethe’s Affinities”, pgs. 371-422, ch. 12: Affinity and Free Energy” [section: “Online Matching”, pgs. 455-64], pgs. 423-68). (preview), (Google books). Morrisville, NC: LuLu.
2. (a) Goethe, Johann von. (1809). Elective Affinities. New York: Penguin Classics.
(b) See: Goethe's human chemistry
(c) Tantillor, Astrida O. (2001). Goethe's Elective Affinities and the Critics. New York: Camden House.
(d) Adler, Jeremy. (1987). “Eine fast magische Anziehungskraft”. Goethe’s “Wahlverwandtschafte” und die Chemie seiner Zeit (“An almost Magical Attraction”). Goethe’s Elective Affinity and the Chemistry of its Time), Munich.
(e) Adler, Jeremy. (1990). "Goethe's use of chemical theory in his Elective Affinities" (ch. 18, pgs. 263-79) in Romanticism and the Sciences - edited by Andrew Cunningham and Nicholas Jardine, New York: Cambridge University Press.
(f) Thims, Libb. (2007). Human Chemistry (Volume Two), (ch. 10: "Goethe's Affinities", pgs. 371-422), (preview), (Google books). Morrisville, NC: LuLu.
3. World's First-ever Textbook on the Chemistry of Love - PR.com (Institute of Human Thermodynamics)
4. Hwang, David. (2001). "The Thermodynamics of Love", Journal of Hybrid Vigor, Issue 1, Emory University.
5. Wilkins, S. (2005). "For Richer or Poorer". MotherJones.com
6. NSHS (2001). "43 Percent of First Marriages Break Up Within 15 Years". Maryland: Hyattsville, US CDC.
7. Gibbs free energy (definition) – The Essential Dictionary of Science (2004), Barnes & Noble.
8. Naumann, Earl. (2001). Love at First Sight – the Stories and Science Behind Instant Attraction, (ch. 2: “The Chemistry of Love”, pgs. 23-42 [35]). Naperville, IL: Casablanca Press.
9. Thims, Libb. (2007). Human Chemistry (Volume Two), (section: “Online Matching”, pg. 458). (preview), (Google books). Morrisville, NC: LuLu.
10. Chang, Raymond. (1998). Chemistry, 6th ed. (ch. 18: “Entropy, Free Energy, and Equilibrium”, pgs. 725-55). New York: McGraw-Hill.
11. ibid (pg. 738).
12. (a) Thims, Libb. (2007). Human Chemistry (Volume One), (section: “Mate desireability factors”, 60-trait table as a function of G(H,S), pgs. 174-178). (preview), (Google books). Morrisville, NC: LuLu.
(b) Todosijević, Bojan, Ljubinković, Snežana, and Arančić, Aleksandra. (2003). “Mate selection criteria: A trait desirability assessment study of sex differences in Serbia”. Evolutionary Psychology, 1: 116-26.
13. Email comments from Gladyshev to Thims on 06/24/08.
14. (a) Fogler, H. Scott. (1992). Elements of Chemical Reaction Engineering, 2nd ed. Englewood Cliffs, N.J.: Prentice Hall P T R.
(b) American chemical engineer H. Scott Fogler, author of the world’s leading textbook on chemical reaction engineering was a teacher of Thims; many parts of the design of algorithmic matching of humans in reactions are modeled on his textbook.

Libb Thims (citations)

Sadi-Carnot — Mon, 01 Dec 2008 17:20:36 CST

In the EoHT wiki, the Libb Thims (citations) page is a listing of the articles, books, magazines, publications, conferences, symposiums, and meetings, etc., where the human thermodynamics, human chemistry, or human molecule theories of American chemical engineer Libb Thims are used, referred to, cited, or mentioned as a reference or point of discourse. These are listed below, originating in 2005 when Thims began to go public with his work:

2009
● Schwartz, Mary Ann A., and Scott, Barbara M. (2009). Marriage and Families: Diversity and Change (6th Edition), (Table 4.1: What is Love – According to Adults, from the IoHT’s 2004 “What is Love?” survey). Prentice Halls.
● Gladyshev, Georgi P. (2009). “Hierarchical thermodynamics and life”. Plenary lecture. Symposium. Fractals and Synergetics. Russian Academy of Science. Moscow, (pgs 11-28).
● Author. (2009). “Book Review: The Human Molecule”, The Chemical Engineer (Jan-Feb), at the request of Claudia Flavell-While, ICE editor.

2008
● Minkin, Viktor, A. and Nikolaenko, N.N. (2008). “Application of Vibraimage Technology and System for Analysis of Motor Activity and Study of Functional State of Human Body”, Biomedical Engineering, Vol. 42, No. 2, pgs. 196-200.
● Ejike, Satch U. (2008). Find a Good Man and Keep Him. Author House.
● Chen, Jing. (2008). “Understanding Social Systems: A Free Energy Perspective”, September, 16. pgs. 1-10. Social Science Resource Network.
● Thims was invited to attend the July 19-20 PodCamp3 Boston (2008) at the Joseph Martin Conference Center at Harvard Medical School.
● Thims' work was presented at the American Association of Physics teachers annual meeting (Chicago, 2008) in the lecture of American chemical engineer and physics teacher Ted Erikson.
● Gladyshev, Georgi P. (2008). “Mechanism of Influence of Foodstuff on Healthy Longevity.” Adv. Gerontology. 2008, v. 21, № 1. P. 34-36.
● Gladyshev, Georgi P. (2008). “Hierarchical Thermodynamics and Life.” Vestnic of National Kazakh University (Almaty). Chemistry. № 2 (50), (pgs 7-12).
● Gladyshev, Georgi P. (2008). “What is Life? Bio-Physical Perspectives”, Knol, Oct.
● Gladyshev, Georgi P. (2008). “Definition of Anti-Aging Values of Natural Foodstuff.” Knol, Nov.
● Gladyshev, Georgi P. (2008). “Hierarchical Thermodynamics: General Theory of Existence and Living World Development” (English), Knol, Dec.

2007
● Aleinikov, Andrie G. (2007). “The Conservation of Extencia: a New Law of Conservation”, Journal of Economics and Economic Education Research, Sept.
● Thims was invited to intend (and to submit a presentation proposals) the 2007 Meeting the Entropy Challenge – an International Thermodynamics Symposium in Honor and Memory of Professor Joseph Henry Keenan at MIT by Italian thermodynamicist Gian-Paolo Beretta.
● Thims' work was presented at the annual American Academy of Anti-Aging Medicine (A4M) World Congress (Las Vegas, 2007) in the lectures of Russian physical chemist Georgi Gladyshev.
● Gladyshev, G.P. (2007). "Hierarchical Thermodynamics - General Theory of Existence: A Living World Development", Becthnk, Vol. 1, pgs. 44-48, Herald of the International Academy of Sciences (Russian Section). ISSN: 1819-5733.
● Gladyshev, Georgi P. (2007). “Leonhard Euler’s Methods and Ideas Live in the Thermodynamics Hierarchical Theory of Biological Evolution.” International Journal of Applied Mathematics and Statistics, Nov., Vol. 11, No. N07, pgs. 52-68.
● Gladyshev, Georgi P. (2007). “The thermodynamic theory of aging in action: medical nutrition recommendations for patients of any age” in Anti-Aging Therapeutics. Ed. Dr.R. Klats and Dr.R. Goldman, Volume IX, Ch. 20, (pgs. 135-152). Chicago: American Academy of Anti-Aging Medicine.
● Gladyshev, Georgi P. (2007). “A Burning Candle Wick is a Model of Living System.” Russia: International Academy of Creative Endeavors.

2006
● Thims' work was presented at the annual American Academy of Anti-Aging Medicine (A4M) World Congress (Chicago, 2006) in the lectures of Russian physical chemist Georgi Gladyshev.
● Gladyshev G. P. (2006). "The Principle of Substance Stability is Applicable to all Levels of Organization of Living Matter" [PDF], International Journal of Molecular Sciences, Vol. 7, pgs. 98-110.

2005
● The HumanThermodynamics.com website was launched on April 27.