In thermodynamics, Gibbs energy flow refers to the movements and couplings of Gibbs free energies involved in the reactions and dynamics of biological activities. The term was used in 2008 by American physical chemist Dilip Kondepudi, in relation to biological systems. In particular, according to Kondepudi, in biological systems, the much discussed “energy flow” through such systems is “Gibbs energy flow” and the thermodynamic force is the change in the Gibbs free energy ΔG during the movement, evolution, or change. [1]

1. Kondepudi, Dilip. (2008). Introduction to Modern Thermodynamics, (chapter 13: Biological Systems, pg. 379, section: 13.3: Gibbs Energy Flow in Biological Systems, pgs. 386-98). John Wiley and Sons.

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